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Recent Submissions

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Cat
(2024-04-30) Anez, Melissa
Kitten pictures!
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Integrated Education Act Strategy and Action Plan
(2024-02) Department of Education
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Statistical Bulletin
(Department of Education, 2019-02) Department of Education
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Lincoln
(2024-03-22)
A cat.
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Doxycycline Prophylaxis for Skin and Soft Tissue Infections in Naval Special Warfare Trainees, United States.
(2024-01-01) Spiro, Jeffrey; Wisniewski, Piotr; Schwartz, Julia; Smith, Alfred G; Burger, Sara; Tilley, Drake H; Maves, Ryan C
In 2015, several severe cases of skin and soft tissue infection (SSTI) among US Naval Special Warfare trainees prompted the introduction of doxycycline prophylaxis during the highest-risk portion of training, Hell Week. We performed a retrospective analysis of the effect of this intervention on SSTI incidence and resulting hospital admissions during 2013-2020. In total, 3,371 trainees underwent Hell Week training during the study period; 284 SSTIs were diagnosed overall, 29 of which led to hospitalization. After doxycycline prophylaxis was introduced, admission rates for SSTI decreased from 1.37 to 0.64 admissions/100 trainees (p = 0.036). Overall SSTI rates remained stable at 7.42 to 8.86 SSTIs/100 trainees (p = 0.185). Hospitalization rates per diagnosed SSTI decreased from 18.4% to 7.2% (p = 0.009). Average length of hospitalization decreased from 9.01 days to 4.33 days (p = 0.034). Doxycycline prophylaxis was associated with decreased frequency and severity of hospitalization for SSTIs among this population.