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    Zoom in DBS
    (Zoom, 2023-04) Mingli Gong
    Welcome to DBS Online Class Home Page
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    Efficacy and safety of Remdesivir treatment for acute respiratory syndrome caused by SARS-COV-2 in patients admitted to a general hospital.
    (2021-02-21) McCarthy, FIONA; Kavanagh, LOCHLYN; Whelan, ENYA; Dunne, CONNOR
    Abstract Background An efficient approach to drug discovery is to test whether existing antiviral drugs are effective in treating viral infections related. SARS-CoV2 is known to belong to the SARS-CoV family and the Middle East CoV Respiratory Syndrome (MERS-CoV). In animal models, administration of GS-5734 significantly reduced the viral load of pulmonary SARS-CoV and improved clinical signs of disease, as well as respiratory function. The objective of our review and metanalisis is to evaluate the efficacy and safety of remdesivir, treatment of acute respiratory syndrome caused by COVID-19 in patients who are admitted to a general hospital Methods PubMed / Medline, Embase, the Cochrane Central Register of Controlled Trials (CENTRAL) and grey literature were searched. We included studies of patients adults over 18 years of age with acute respiratory syndrome withSARS-CoV2. The primary objective was to assess the rate mortality with remdesivir vs placebo. The secondary objective was to assess the rate general and severe side effects. Results Overall mortality was lower in the group receiving remdesivir in comparison to the placebo group (OR 0.65; 95% CI, 0.44-0.96; I2 55%). The risk of adverse events was (OR 1.01; 95% CI, 0.79-1.28; I2 0%) and that of severe adverse events was (OR 0.71; 95% CI, 0.55-0.92; I2 0%) remdesivir compared to placebo. Conclusions The use of remdesivir for the treatment of SARS-COV2 acute respiratory syndrome in patients admitted to a general hospital is based on a weak recommendation, because the quality of the evidence is low.
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    Los osos ortodoxos
    (Andinos de fomento, 2020-01-20) Levenson, Martin
    Los osos son uno de los grupos de mamíferos más carismáticos que existen. Son personajes de mitos, cuentos y fábulas, cine y televisión, y han sido exaltados por su gracia, como el oso panda gigante, o por su majestuosidad, como el oso polar. Pero la realidad es otra: en su mayoría, están en peligro de extinción a causa de la pérdida del hábitat, la caza ilegal y el calentamiento global.
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    blue smile
    (2020-11-12)
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    blue circle
    (2020-11-12)
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    ocean
    (2020-11-12)
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    sky
    (2020-11-12)
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    blue
    (2020-11-12)